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3D-MRE and 2D-MRE for Assessing Cirrhosis and Portal Hypertension

Recruitingn/aAges 18 Years - 75 YearsAllShengjing Hospital
NCT06205992 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

How to construct a novel, non-invasive, accurate, and convenient method to achieve prediction of hepatic venous pressure gradient (HVPG) is an important general problem in the management of portal hypertension in cirrhosis. We plan to compare the ability of three demensional-magnetic resonance elastography (3D-MRE) to two demensional-magnetic resonance elastography (2D-MRE) to establish a risk stratification system and perform tailored management for portal hypertension in cirrhosis.

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📋 Eligibility rules (as published)
Inclusion Criteria: 1. age \> 18 years old 2. confirmed cirrhosis (laboratory, imaging and clinical symptoms) 3. with 3D-MRE and 2D-MRE within 1 month prior to HVPG measurement 4. written informed consent Exclusion Criteria: 1. any previous liver or spleen surgery 2. liver cancer; chronic acute liver failure 3. acute portal hypertension 4. unreliable HVPG, 3D-MRE or 2D-MRE results due to technical reasons 5. with liver interventional therapy between HVPG and MRE
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What it tests

  • 3D-MRE
  • HVPG
  • 2D-MRE
  • HVPG
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Where

1 site
Shengjing Hospital of China Medical University
Shenyang, China
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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