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EXercise Cardiac Magnetic Resonance Assessment of Left Atrial Mechanics Following Ablation

Recruitingn/aAges 18 Years - anyAllVirginia Commonwealth University
NCT06212791 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Longitudinal, observational cohort study to evaluate changes in left atrial (LA) reservoir function during exercise and overall exertional capacity in patients following catheter ablation for paroxysmal atrial fibrillation (AF).

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📋 Eligibility rules (as published)
Inclusion Criteria: * Age ≥18 years * Diagnosis of paroxysmal AF * Left ventricular ejection fraction ≥50% * Scheduled for catheter ablation * Able to speak, hear, and read English * Willing and able to provide informed consent Exclusion Criteria: * Persistent or permanent AF * Prior ablation (catheter based or surgical) for AF * Significant sinus node dysfunction * Implanted pacemaker or defibrillator * Contraindication to or inability to complete cardiovascular magnetic resonance study * Contraindication to or inability to complete exercise testing * Chronic kidney disease with estimated glomerular filtration rate \<30 mL/min/1.73m2 * Severe left ventricular hypertrophy * Unrelated cardiomyopathy that is expected to limit exercise capacity, including but not limited to: * Hypertrophic cardiomyopathy * Cardiac amyloidosis * Constrictive pericarditis * Pulmonary arterial hypertension * Prior cardiac surgery * Active pregnancy
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What it tests

  • Self- Report Evaluation-Duke Activity Status Index
  • Self- Report Evaluation Atrial Fibrillation Effect on Quality of Life Questionnaire
  • Cardiopulmonary exercise test (CPET)
  • Transthoracic echocardiogram
  • Ambulatory cardiac rhythm assessment
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Where

1 site
Virginia Commonwealth University
Richmond, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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