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Effect of Honey For CIN II

RecruitingPhase 1, Phase 2Ages 18 Years - 40 YearsFemaleZuyderland Medisch Centrum
NCT06219018 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The following hypothesis is tested: Medical grade honey in CIN II causes a higher clearance of the hr-HPV virus and an increase in the normalization of CIN II lesions compared to expectant management.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Women 18-40 years * Primary CIN II confirmed histologically in the biopsy on colposcopic examination * Sufficient mastery of the Dutch language Exclusion Criteria: * Simultaneous abnormality in columnar epithelial cells (AIS). * Hr-HPV negative cytology * Immunosuppressant use/Autoimmune disease (HIV, CVID) * History of cervical carcinoma or previous treatment for CIN (LLETZ or imiquimod) * Pregnancy or the intention to become pregnant during the study period * Legal incompetence * Known allergies to honey
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What it tests

  • Medical grade honey formulation (MGH) (L-Mesitran®)
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Where

2 sites
Zuyderland MC
Heerlen, Netherlands
Maastricht University Medical Centre+
Maastricht, Netherlands
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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