🌐 EnglishEN

AI Cure is a research tool showing open data. Not medical advice. Discuss with your doctor. Terms

← Trials
🧪

Short-term And Longer-term Cognitive Impact Of Neurochecks

RecruitingNAAges 18 Years - 100 YearsAllUniversity of California, San Diego
NCT06219889 on ClinicalTrials.gov ↗
💬

In plain words

What the trial is, and whether it could suit you

The proposed research plan seeks to understand the impact of sleep disruption in the Neurological Intensive Care Unit (ICU) on older patients with acute brain injury (ABI). In current practice, the neurocritical care community performs frequent serial neurological examinations ("neurochecks") in an effort to monitor patients for neurological deterioration following brain injury. Many neurocritical patients are older and/or cognitively fragile, and delirium is common. Although ICU delirium is multifaceted, frequent neurochecks may represent a modifiable risk factor if the investigators can better understand the risks and benefits of various neurocheck frequencies. This project will randomize patients with acute spontaneous intracerebral hemorrhage (ICH) to either hourly (Q1) or every-other-hour (Q2) neurochecks and evaluate the impact of neurocheck frequency on delirium. Second, longer-te

Sign in to get the eligibility rules as simple questions to take to your doctor.

Sign in
📋 Eligibility rules (as published)
Inclusion Criteria (Part 1): 1. Adult patients (age \>18 years) with spontaneous acute \<45cc in volume with radiographic and clinical stability for ≥6 hours following admission to the ICU. These criteria are based on the literature and experience of the investigative team. 2. Additional intraventricular hemorrhage (with or without external ventricular drain) is allowable. 3. Only first admission to the NeuroICU during the hospitalization will be eligible. Inclusion criteria (Part 2): a. any patient included in part 1 alive at 6 months post-discharge Exclusion Criteria: 1. Patients with unstable intracranial bleeding 2. Patients with known history of intracranial neurological injury 3. Pre-existing cognitive impairment (known or highly suspected based on family-provided history, Activities of Daily Living Questionnaire) 4. Pre-existing diagnosed sleep disorder 5. Comatose or heavily sedated 6. Death expected within 30 days or other terminal illness 7. ICH score \>4 (equivalent to mortality risk \>72%) 8. Pregnancy 9. Incarcerated 10. Non-English or non-Spanish speaking
💊

What it tests

  • Frequency of neurochecks
📍

Where

1 site
UC San Diego Health
San Diego, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
🛡️

AI Cure shows public evidence (Open Targets, ClinicalTrials.gov, PubMed, openFDA, DepMap, AlphaFold) with its source, and AI summaries that cite it — not medical advice and not a cure. Treatment decisions belong with your doctor. Research ideas are shared only with approved researchers and labs, who can test them. In an emergency call your local emergency number (112 in India and Europe, 911 in the US). AI Cure Terms of Use · Privacy