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Structural Racism, Reward Related Decision Making and Substance Use Risk

Recruitingn/aAges 11 Years - 14 YearsAllColumbia University
NCT06221839 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The goal of this observational study, which has a pilot phase (R61) and a second, larger phase (R33), is to learn about the impact of indicators of structural racism (SR) on substance use risk in Puerto Rican adolescents living in the mainland US and in Puerto Rico. To do this, we will look at how indicators of SR relate to brain structure, brain function during reward-related choices, belief in a just world, and substance use risk indicators in Puerto Rican adolescents living in the mainland US (mostly in New York) and in Puerto Rico (mostly in San Juan). We are currently focused on the R61 (pilot) phase. This pilot phase aims to answer the question: Is there a relationship between indicators of SR and brain structure, brain function during reward-related decision making, and belief in a just world? If we are able to establish a relationship between SR indicators and outcomes, we will c

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📋 Eligibility rules (as published)
Inclusion Criteria: 1. The adolescent participant is a biological or non-biological child of a member of the original Boricua Youth Study (BYS) sample. 2. The adolescent is between the ages of 11 to 14.5 at the time of recruitment, and 11 to \<15 at the time of study participation. 3. If the parent/caregiver is not an original BYS member, they have provided a consent to contact form. 4. Parent/caregiver is between the ages of 18-64.5 at the time of recruitment and 18 to \<65 at the time of study participation Exclusion Criteria: 1. Major neurological disorder (e.g. seizure disorder) or cognitive impairment (e.g., moderate to severe Autism Spectrum Disorder, Intellectual Disability) 2. Exclusion criteria for the MRI scan only: MRI contraindications (e.g., irremovable metal on the body, pacemaker, braces, etc.; pregnancy (while required by NYSPI).
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What it tests

  • Not listed
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Where

2 sites
Columbia University Irving Medical Center
New York, United States
University of Puerto Rico, Medical Sciences Campus
San Juan, Puerto Rico
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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