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Anticoagulation and Inflammation Monitoring in Patients After Heart and Vascular Interventions

Recruitingn/aAges 18 Years - anyAllMedical University Innsbruck
NCT06222866 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The goal of this prospective observational study is to evaluate the most appropriate anticoagulation monitoring tool for unfractionated heparin (UFH), by comparison of different monitoring modalities in relation to adverse events occurrence (thrombosis/bleeding). The main study questions are: * What is the most appropriate anticoagulation monitoring tool (ACT, aPTT, viscoelastic tests (ROTEM), and anti-Xa) for UFH * What is the incidence of adverse events associated with anticoagulation and inflammation after heart and vascular interventions * Is there an association of available anticoagulation thresholds and monitoring tests with bleeding and/or thrombosis occurrence * Is there an association of inflammation with delirium Secondary study objectives include: * Association of anticoagulation levels as measured by ACT, aPTT, viscoelastic tests (ROTEM), and anti-factor-Xa with adverse

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📋 Eligibility rules (as published)
Inclusion Criteria: * Age: \> 17 years * Informed written consent * Scheduled for cardiac intervention where the use of UFH is expected (elective surgery) * Scheduled for vascular intervention when the need for perioperative anticoagulation is expected (elective surgery) * Patients receiving ECMO support Exclusion Criteria: * Patients that are known to be pregnant * Known participation in other interventional clinical trial
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What it tests

  • Anticoagulation monitoring
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Where

1 site
Medical University Innsbruck
Innsbruck, Austria
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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