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A Study to Evaluate the Efficacy of AXS-05 Compared to Bupropion in Preventing the Relapse of Depressive Symptoms

RecruitingPhase 4Ages 18 Years - 65 YearsAllAxsome Therapeutics, Inc.
NCT06223880 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This is a randomized, double-blind, active-controlled, multi-center study to evaluate the efficacy of AXS-05, compared to bupropion, in preventing the relapse of depressive symptoms in subjects with major depressive disorder (MDD) who have responded to treatment with AXS-05.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Currently meets DSM-5 criteria for diagnosis of MDD without psychotic features * Current major depressive episode of at least 4 weeks in duration Exclusion Criteria: * Previously participated in another clinical study of AXS-05; received any investigational drug or device treatment within 30 days of (Screening) Visit 1, or has been prescribed Auvelity. * Unable to comply with study procedures * Medically inappropriate for study participation in the opinion of the investigator
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What it tests

  • AXS-05
  • Bupropion
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Where

40 sites
Clinical Research Site
Bellflower, United States
Clinical Research Site
Lafayette, United States
Clinical Research Site
Oceanside, United States
Clinical Research Site
Redlands, United States
Clinical Research Site
Riverside, United States
Clinical Research Site
San Diego, United States
Clinical Research Site
Upland, United States
Clinical Research Site
Brandon, United States

…and 32 more on ClinicalTrials.gov.

🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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