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โ† Trials
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Comparison of Catecholamine Concentrations in Venous Blood During Selective Adrenal Artery Embolization

Recruitingn/aAges 18 Years - anyAllFirst Affiliated Hospital of Chengdu Medical Collโ€ฆ
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In plain words

What the trial is, and whether it could suit you

To explore the relationship between perioperative blood pressure and catecholamine concentrations in adrenal venous blood and peripheral venous blood in hypertensive patients with primary aldosteronism (PA) who underwent percutaneous selective adrenal artery embolization (SAAE). In order to elucidate the related phenomena and possible mechanisms of blood pressure fluctuations caused by SAAE treatment in hypertensive patients with PA.

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๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: 1. Age โ‰ฅ18 years with no gender restrictions. 2. Adherence to the "Primary Aldosteronism" Diagnosis and Treatment Guidelines, confirmed diagnosis of primary aldosteronism following rigorous drug washout, and identification as either aldosteronoma or idiopathic aldosteronism via adrenal vein blood sampling. 3. Blood pressure metrics that satisfy any of the subsequent conditions: a) Clinic-recorded blood pressure โ‰ฅ140/90mmHg; b) 24-hour ambulatory blood pressure monitoring results displaying average blood pressure \>130/80 mmHg or daytime readings \>135/85 mmHg. 4. Adrenal CT scan revealing adrenal hyperplasia, nodular formations, or no significant morphological deviations. 5. Hypertension history surpassing a duration of 6 months. 6. Prior to screening, patients or their lawful guardians must provide a signed informed consent, sanctioned by the ethics committee. Exclusion Criteria: 1. Patients diagnosed with primary hypertension or secondary hypertension attributed to other etiologies. 2. Female participants who are presently pregnant, lactating, or with intentions to conceive within the forthcoming year. 3. Presence of significant systemic diseases, with particular attention to hepatic and renal dysfunction. 4. Pronounced allergic reaction to contrast agents. 5. Any other serious systemic diseases with a life expectancy of less than 12 months. 6. Participants concurrently enrolled or expressing interest to participate in other clinical trials, the outcomes of which could potentially influence the results of the current study. 7. The researcher's discretion deems the subject inappropriate for inclusion in the study for any given reason.
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What it tests

  • Selective adrenal artery embolization
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Where

1 site
The First Affiliated Hospital of Chengdu Medical College
Chengdu, China
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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