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Famotidine and Antacids for Treatment of Dyspepsia

RecruitingPhase 4Ages 18 Years - anyAllStony Brook University
NCT06241183 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The aim of this study is to compare intravenous famotidine, an H2 receptor antagonist, and Maalox/ Mylanta, an oral antacid, in treatment of dyspepsia in the emergency department. The goal of this study is to reduce patients' pain based on the verbal numerical pain scale. The anticipated outcome is for pain levels in both groups to decrease. It is expected that antacids will improve symptoms more quickly and to a greater degree within an hour of taking medication based on the results of similar studies.

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📋 Eligibility rules (as published)
Inclusion Criteria: 1. Subject Age ≥ 18 years of age 2. Patient diagnosed with dyspepsia 3. Present at the ED with upper abdominal pain score of at least 3 Exclusion Criteria: 1. Hypersensitivity to an ingredient in Maalox/ Mylanta or Famotidine 2. Moderate to Severe Renal Insufficiency (precaution) 3. Kidney Failure 4. Pregnant or Nursing 5. Verbal pain score less than 3 6. Inability to tolerate oral medications 7. Bowel Obstruction 8. Proton pump inhibitor within 2 hours of study treatment
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What it tests

  • Intravenous Famotidine
  • Oral Maalox/ Mylanta
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Where

1 site
Stony Brook University Hospital
Stony Brook, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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