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A Study of Maribavir in Adults With Kidney Failure Who Have a Cytomegalovirus (CMV) Infection After Transplantation

Recruitingn/aAges 18 Years - anyAllTakeda
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In plain words

What the trial is, and whether it could suit you

The main aim of this study is to assess the safety of maribavir in adults with severe CKD or comorbid ESRD including participants on artificial filtering of the kidney (dialysis) or the blood (hemodialysis). In this study, already existing data will be collected from the participant's medical records. The study will only review data collected as part of the normal clinical routine and will not impact the standard medical care and treatment of participants.

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * Adults more than and equal to (โ‰ฅ) 18 years of age at index date. * Diagnosis of comorbid ESRD or comorbid severe CKD prior to the index date. * If ESRD (including participants on peritoneal dialysis or hemodialysis): participant diagnosed with ESRD confirmed by an estimated glomerular filtration rate (eGFR) less than (\<) 15 milliliters per minute per 1.73 square meters (mL/min/1.73m\^2). * If severe CKD: participant diagnosed with severe CKD confirmed by an eGFR of 15 to \<30 mL/min/1.73m\^2 at index. * Participant has undergone solid organ transplant (SOT) or hematopoietic stem cell transplantation (HSCT) before index date. * Participant was diagnosed with refractory (with or without resistance) CMV during the latest post-transplant period. * Participant initiated treatment with maribavir in routine practice within the eligibility period and received at least 1 dose of maribavir. * Informed consent provided (where required by local regulations) before data collection commences. Exclusion Criteria: There are no exclusion criteria for this study.
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What it tests

  • No Intervention
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Where

25 sites
Hopital Erasme - PPDS
Anderlecht, Belgium
UZ Leuven - PPDS
Leuven, Belgium
North Estonia Medical Centre Foundation
Tallinn, Estonia
Tartu University Hospital
Tartu, Estonia
CHU de Brest - Hopital La Cavale Blanche
Brest, France
CHU de Bordeaux - Hopital Pellegrin
Bordeaux, France
CHU de Montpellier - Hopital Lapeyronie
Montpellier, France
CHU de Grenoble Alpes - Hopital Michallon
La Tronche, France

โ€ฆand 17 more on ClinicalTrials.gov.

๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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