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Bipedal vs. Unipedal Exercises in Chronic Ankle Instability

RecruitingNAAges 18 Years - 50 YearsAllIstanbul University - Cerrahpasa
NCT06244511 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Ankle sprain is a commonly encountered condition in clinical practice, constituting approximately 15-30% of all musculoskeletal injuries. Long-term studies have demonstrated that up to 73% of patients experience at least one more ankle sprain following an acute ankle sprain. Inadequate treatment of acute ankle instability can lead to chronic ankle instability (CAI) in 30-70% of cases. Treatment approaches for CAI are classified into conservative and surgical methods. Typically, conservative treatment is initially employed to address proprioceptive deficits and static impairments. Passive, unidirectional treatments such as injections, electrotherapy, and ice, which do not target muscle strength, kinetic chain, tendon capacity, and cortical control, are reported to be insufficient or ineffective in treating CAI, relying solely on symptomatic relief. Therefore, therapeutic exercises are fu

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📋 Eligibility rules (as published)
Inclusion Criteria: * The documented unilateral ankle instability confirmed through clinical examinations (drawer test, talar tilt test) and MRI in cases requiring differential diagnosis. * A history of an initial ankle sprain occurring at least 6 months ago. * The presence of a recurrent sense of giving way that started at least 6 months ago and has been intermittently persistent. Exclusion Criteria: * Presence of a history of previous surgery in the lower extremity. * Identification of organic and non-organic lesions such as cartilage injuries, periarticular tendon tears, and impingement syndromes. * The existence of a fracture accompanying instability in the foot-ankle. * Presence of congenital deformities in the foot-ankle. * Diagnosis of talus osteochondral lesion. * Diagnosis of ankle arthritis. * Presence of medial ligament lesion. * Existence of peripheral neuropathy. * Presence of additional rheumatological diseases. * Regular moderate-level exercise for at least 3 days a week in the last 6 months.
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What it tests

  • Early Bipedal Exercise
  • Late Bipedal Exercise
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Where

1 site
Acibadem Mehmet Ali Aydinlar University
Istanbul, Turkey (Türkiye)
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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