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Study of Diosmin for the Treatment of Digital Ulcers in Systemic Sclerosis

RecruitingNAAges 18 Years - anyAllPrimus Pharmaceuticals
NCT06256575 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This study is performed to consider the safety and healing ability of diosmin in patients with systemic sclerosis (scleroderma) and open sores on their fingers (digital ulcers). Two (2) out of three (3) participants will receive active product. The participants will have four (4) visits over eight (8) weeks. Physical exams and photos will be performed. A variety of questions will be asked describing level of pain and lifestyle changes.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Diagnosis of systemic sclerosis (scleroderma) * At least one "active" digital ulcer * Medication for systemic sclerosis unchanged for 30 days Exclusion Criteria: * Infection or gangrene in ulcer * Citrus allergy * Unstable heart, kidney, or liver disease * Active infection of any type * Current cancer treatment or uncured cancer * Pregnancy or breast feeding
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What it tests

  • Diosmin
  • Placebo
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Where

5 sites
University of Calgary
Calgary, Canada
Dalhousie University
Halifax, Canada
Saint Joseph Health Care Centre
London, Canada
The Ottawa Hospital
Ottawa, Canada
Mount Sinai Health System
Toronto, Canada
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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