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Virtual Incentive Treatment for Alcohol

RecruitingNAAges 18 Years - anyAllWashington State University
NCT06265506 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The overall objective of this program of research is to utilize phosphatidylethanol (PEth), a blood-based biomarker that can detect alcohol use for up to 28 days to deliver a feasible telehealth-based 26-week CM intervention. This study will test a telehealth PEth-based CM model in a sample of adults with AUD (n=200), recruited via online platforms by randomizing individuals to six months of 1) an online cognitive behavioral therapy for AUD (CBT4CBT) and telehealth PEth-based CM (CM condition) or 2) CBT4CBT and reinforcers for submitting blood samples (no abstinence required) (control condition). Investigators will assess group differences in PEth-defined abstinence and regular excessive drinking (PEth \>= 200 ng/mL), and alcohol-related harms (e.g., smoking, drug use). This study will address important gaps in CM research by assessing outcomes during a 12-month follow-up, which is much

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📋 Eligibility rules (as published)
Inclusion Criteria: 1. Had 2 heavy drinking episodes (assigned male at birth \> 4 standard drinks (SDs), assigned female at birth \> 3 SDs) or ≥14 SDs in the prior 14 days verified by PEth 16:0/18:1 biomarker \> 20 ng/mL (indicates at least 2 heavy drinking episodes in past two weeks); 2. Have a DSM-5 diagnosis of a current AUD as assessed by the Structured Clinical Interview for DSM-5; 3. 18+ (individuals over 65 will be assessed for cognitive impairments) 4. Are not receiving treatment for AUD 5. Are able to complete virtual study visits via Zoom Exclusion Criteria: 1. have a current diagnosis of severe substance use disorder (other than AUD, tobacco, and cannabis); 2. PEth biomarker ≤ 20 ng/mL (indicates no heavy drinking in past month) 3. inability to provide informed consent based on the UBACC or MacCAT-CR; 4. alcohol withdrawal-related seizure or hospitalization in prior 12 months; 5. psychiatrically or medically unsafe to participate, as assessed by the PI; and/or 6. currently enrolled in alcohol treatment or another alcohol treatment study.
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What it tests

  • Contingency Management
  • Computer Based Training for Cognitive Behavioral Therapy for AUD (CBT4CBT)
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Where

1 site
Washington State University
Spokane, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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