🌐 EnglishEN

AI Cure is a research tool showing open data. Not medical advice. Discuss with your doctor. Terms

← Trials
🧪

Oxytocin Rest to Reduce Cesarean Delivery

RecruitingNAAges 18 Years - 55 YearsFemaleChristiana Care Health Services
NCT06268431 on ClinicalTrials.gov ↗
💬

In plain words

What the trial is, and whether it could suit you

Prolonged labor is usually managed with continuous oxytocin infusion. "Oxytocin rest" has been proposed as a strategy to resolve protracted labor in patients who have received continuous oxytocin without progress. This strategy involves discontinuing oxytocin then restarting infusion after a period of time, under the theory that washout of the oxytocin receptor will strengthen uterine contractions to improve labor progress. "Oxytocin rest" is performed on labor and delivery units across the United States. Yet, there is no randomized or prospective data to support the practice. The purpose of this study is to assess whether oxytocin rest of 60 minutes in patients with prolonged labor reduces risk for cesarean delivery.

Sign in to get the eligibility rules as simple questions to take to your doctor.

Sign in
📋 Eligibility rules (as published)
Inclusion Criteria: * ≥18 years of age * Singleton gestation in vertex presentation * ≥36 weeks gestation * Prolonged latent labor, defined as cervical dilation \<6cm after ≥8 hours since rupture of membranes and on continuous oxytocin Exclusion Criteria: * Not meeting the above criteria * Any contraindication to continuous oxytocin at time of randomization * Cesarean section anticipated by the clinical team at time of randomization (for any reason excepting labor dystocia) * \>18 hours between rupture of membranes and randomization * Known intraamniotic infection at randomization * Fetal demise * Any contraindication to vaginal delivery * Maternal eclampsia
💊

What it tests

  • Oxytocin rest
📍

Where

1 site
ChristianaCare Health System
Newark, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
🛡️

AI Cure shows public evidence (Open Targets, ClinicalTrials.gov, PubMed, openFDA, DepMap, AlphaFold) with its source, and AI summaries that cite it — not medical advice and not a cure. Treatment decisions belong with your doctor. Research ideas are shared only with approved researchers and labs, who can test them. In an emergency call your local emergency number (112 in India and Europe, 911 in the US). AI Cure Terms of Use · Privacy