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A Prospective Study on the Treatment of cLM Based on ICG Imaging

RecruitingNAAges 30 Days - 16 YearsAllNanjing Children's Hospital
NCT06275022 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The goal of this prospective randomized controlled study is to explore the role of indocyanine green-fluorescence imaging in management of cystic lymphatic malformation.. To clarify the application value of indocyanine green-fluorescence imaging in both diagnosis and treatment of cystic lymphatic malformation (cLM) in children, is helpful for exploring pathogenesis of cLM, and providing a clearer scientific basis for subsequent surgical intervention. It also provides alternative for the future diagnosis and treatment of cLM. Participants will receive indocyanine green-fluorescence imaging before operation, while the patients in control group will receive traditional operation. Researchers will compare difference in curative effect between two groups.

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📋 Eligibility rules (as published)
Inclusion Criteria: (1) no previous intervention; (2) cLM diagnosed by pretreatment magnetic resonance imaging (MRI); (3)3 to 6 months post-treatment follow-up; (4) Superfacial cLM Exclusion Criteria: (1) history of iodine allergy; (2) syndromic cLM ; (3) severe liver and kidney dysfunction; (4) intralesional hemorrhage; (5) intralesional infection
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What it tests

  • Inflow occlusion with perforation of septation and sclerotherapy
  • Perforation of septation and sclerotherapy
  • Indocyanine green-guided partial resection and sclerotherapy
  • Partial resection and sclerotherapy
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Where

1 site
Children's hospital of Nanjing medical university
Nanjing, China
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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