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H. Pylori Screen-and-treat Study in a Population of Young Adults

Recruitingn/aAges 30 Years - 34 YearsAllUniversity of Latvia
NCT06275204 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Gastric cancer remains a major challenge to public health on a global scale. H. pylori related cancer burden contributes to the largest proportion of cancer cases attributable to infections in Europe. Considering its absolute burden and persisting disparities, in addition to the substantial prevalence of H. pylori infection worldwide that is treatable, gastric cancer is a logical target for urgent action for prevention. Population-based H. pylori test-and-treat has therefore been proposed as a strategy for gastric cancer prevention. To fill the gaps in knowledge about gastric cancer prevention through H. pylori screening and eradication in younger adults, a study of a population-based H. pylori test-and-treat strategy in Ireland, Croatia, Latvia, Poland, Romania and Slovenia. Main goals of this study are to assess future program processes, feasibility, acceptability and effectiveness. I

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📋 Eligibility rules (as published)
Inclusion Criteria: * Young adults (generally 30 - 34 years of age) Exclusion Criteria: * Patients with mental or developmental limitations who cannot provide a fully-informed consent to participate (based on the assessment from research or patient's personal physician team) * Previously treated H. pylori infection * History of partial or total gastric resection due to benign or malign lesions
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What it tests

  • Bismuth-based quadruple therapy
  • Levofloxacin-based quadruple therapy
  • Standard triple therapy
  • Levofloxacin-based triple
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Where

7 sites
University Hospital Centre Zagreb
Zagreb, Croatia
Clinical Hospital Center Rijeka
Rijeka, Croatia
Beacon Hospital
Dublin, Ireland
Clinical and Preventive Medicine of the University of Latvia
Riga, Latvia
Wroclaw Medical University
Wroclaw, Poland
Iuliu Hatieganu University of Medicine and Pharmacy
Cluj-Napoca, Romania
National Institute of Public Health, Slovenia
Ljubljana, Slovenia
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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