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Long-Term Follow-up Study for Subjects With CHB Previously Treated With Imdusiran (AB729)

Recruitingn/aAges 20 Years - 70 YearsAllArbutus Biopharma Corporation
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In plain words

What the trial is, and whether it could suit you

This is a long term follow-up study for chronic hepatitis B (CHB) subjects who have received imdusiran treatment in a prior clinical trial, stopped NA therapy during that trial, and remain off therapy. Subjects may enroll after completing the end of study visit (baseline visit within 12 weeks ยฑ 1 week from the end of study \[EOS\] visit) from their imdusiran clinical trial (the "parent study"). No interventions will be performed in this study other than blood sample collections, review of current medications, and reporting of any adverse events related to study procedures or NA therapy if restarted. Study participation will be for approximately 2 years (to complete a total of at least 3 years of follow-up while off NA therapy, inclusive of parent study participation).

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Key Inclusion Criteria: * Have participated in a prior imdusiran clinical trial, * Have discontinued NA therapy in that trial and remain off NA therapy, * Have completed less than 3 years of follow-up visits after NA discontinuation in the parent study. * Have the ability to review and provide signed informed consent which includes compliance with all protocol-specified visit schedules and requirements. Exclusion Criteria: * Not applicable
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What it tests

  • Non-interventional
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Where

18 sites
Research and Education Inc.
San Diego, United States
University of Miami Miller School of Medicine
Miami, United States
Infectious Disease Care
Hillsborough, United States
The Alfred Hospital
Melbourne, Australia
Fiona Stanley Hospital
Murdoch, Australia
Prince of Wales Hospital
Shatin, Hong Kong
Queen Mary Hospital
Hong Kong, Hong Kong
Arensia Exploratory Medicine Moldova
Chisinau, Moldova

โ€ฆand 10 more on ClinicalTrials.gov.

๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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