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An Observational Study Called FINEROD to Learn More About the Use of the Treatment Finerenone Including How Safe it is and How Well it Works Under Real-world Conditions

Recruitingn/aAges 18 Years - anyAllBayer
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In plain words

What the trial is, and whether it could suit you

This is an observational study, in which data from people in Asia and in the United States with chronic kidney disease (CKD) together with type 2 diabetes (T2D) are studied. The participants in this study are already receiving the study treatment finerenone as part of their regular care from their doctors. In observational studies, only observations are made without specified advice or interventions. CKD is a long-term progressive decrease in the kidneys' ability to work properly. In people with T2D, the body does not make enough of a hormone called insulin, or does not use insulin well enough. The resulting high blood sugar levels can cause damage to the kidneys. CKD often occurs together with T2D or as a consequence of T2D. Finerenone works by blocking certain proteins, called mineralocorticoid receptors. By doing this, it may reduce damage to kidneys, heart and blood vessels. Finereno

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * A minimum of 12 months of continuous enrolment in the databases with medical and pharmacy coverage measured as continuously receiving medical care from health providers contributing to the EHR or claims system, depending on the database used * No recorded prescription for finerenone in the 12 months prior to the index date * Age of 18 years or older as of the index date * Evidence of T2D at any point before (and including) the index date. * CKD stages 2-4 related to eligibility will be defined according to the presence of the following criteria at any point before (and including) the index date: * A diagnosis code indicating CKD stage 2, 3, 4 or stage unspecified * two UACR tests results โ‰ฅ 30 mg/g separated by at least 90 days and by not more than 540 days * two different eGFR test results โ‰ฅ 15 mL/min/1.73 m2 AND \< 60 mL/min/1.73 m2 separated by at least 90 days and by not more than 540 days Exclusion Criteria: \- Kidney failure defined as follows: * Two different eGFR test results \< 15 mL/min/1.73 m2 separated by at least 90 days and by not more than 540 days; * Dependence on dialysis (at least 3 sessions over at least 90 days during the baseline period); * A diagnosis code indicating kidney failure or CKD stage 5; Kidney transplant
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What it tests

  • Finerenone (BAY 94-8862)
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Where

4 sites
Many Locations
Multiple Locations, United States
Bayer
Berlin, Germany
Many Locations
Multiple Locations, Japan
Many Locations
Multiple Locations, Taiwan
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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