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PRP Versus PRF Versus Conventional Treatment in Chronic Non-healing Skin Ulcers

RecruitingNAAges 18 Years - 65 YearsAllKafrelsheikh University
NCT06281483 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

To compare the therapeutic efficacy of PRP and PRF: two relatively newer modalities in the management of chronic non-healing ulcers versus conventional treatment.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Patients presenting with cutaneous ulcers greater than six weeks of duration and a size ranging between 0.5 and 10 cm, having a normal platelet count and hemoglobin \>10 gm%. Exclusion Criteria: * Patients with known bleeding disorders, and/or on oral anticoagulant therapy, uncontrolled diabetes, proven malignancy. * Patients who are pregnant or lactating. * Patients with actively infected ulcers, clinically defined by purulent discharge, green discoloration or fever, or positive culture, ulcers with exposed bone with no underlying granulation tissue, HIV, HCV, HBV patients. * Patients who are with unrealistic expectations and unwilling to give consent for treatment or photography.
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What it tests

  • platelet-rich plasma
  • platelet-rich fibrin
  • Surgical debridement, normal saline washing and dressing coverage
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Where

1 site
Badr Hospital - Helwan University and Kafrelseikh University Hospital
Cairo, Egypt
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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