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Early Prediction and Warning for Cardiotoxicity Due to Anthracycline-Based Breast Cancer Chemotherapy

Recruitingn/aAges 18 Years - 80 YearsFemaleFirst Hospital of China Medical University
NCT06282796 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This multicenter clinical study aims to build an intelligent and accurate diagnosis and dynamic prediction and early warning model of cardiotoxicity due to anthracycline-based breast cancer chemotherapy, clarify the value of the early warning model in guiding the targeted prevention of myocardial protection, providing an important theoretical basis for reducing the mortality rate of breast cancer and improving the prognosis.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Age ≥18 years * Histologically or cytopathological confirmed stage I-III HER2+ breast cancer, scheduled to receive consecutive anthracycline chemotherapy or subsequent sequential trastuzumab targeted therapy * LVEF≥53% before chemotherapy Exclusion Criteria: * life expectancy ≤12 months * Participating in other ongoing oncology clinical trials * Prior treatment with anthracyclines or chest radiation therapy * Pregnant or lactating women * Ultrasound images of the heart are of very poor quality
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What it tests

  • Echocardiography
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Where

5 sites
Fujian Cancer Hospital
Fuzhou, China
Dalian Friendship Hospital
Dalian, China
Dalian Municipal Central Hospital
Dalian, China
Liaoning Cancer Hospital & Institute
Shenyang, China
The Third People's Hospital Of Chengdu
Chengdu, China
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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