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Pharmacological and Non-pharmacological Treatment Effects on Children With Different Predicted Myopia Progression Rate

RecruitingNAAges 7 Years - 9 YearsAllThe Hong Kong Polytechnic University
NCT06282848 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The goal of this clinical trial is to compare pharmacological and non-pharmacological treatment effects on the children with different predicted myopia progression rate measured by modified multifocal electroretinogram. The main questions it aims to answer are: * the effectiveness of using 0.05% atropine and prescribing DIMS lens for myopia control in children with different myopia progression rates * the contribution of L/M cones in juvenile myopia progression and changes of retinal activities under atropine and DIMS treatment. Participants will have baseline and follow-up eye examinations and given either pharmacological treatment with 0.05% atropine or non-pharmacological treatment with DIMS lens for myopia control. Researchers will compare the changes of refractive errors and axial length after different types of interventions and investigate the relations between the parameters o

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📋 Eligibility rules (as published)
Inclusion Criteria: * be aged between 7 and 9 years * have no reported eye disorder and no family history of eye disease * be able to participate in this study for 24 months * not have any current or history of epilepsy * not have any current or history of asthma * have refractive error between 0.50 D and 4.00 D and less than 1.50D of astigmatism with best corrected visual acuity of LogMAR 0.0 or better * have no detected eye diseases or disorders after eye examination, except myopia
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What it tests

  • Atropine 0.05%
  • DIMS lens
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Where

1 site
School of Optometry, Hong Kong Polytechnic University
Hong Kong, Hong Kong
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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