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Interaction Between Early Trauma and Odor-induced Dopamine Release

RecruitingNAAges 18 Years - 30 YearsAllHôpital le Vinatier
NCT06284382 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This prospective, double-blind, parallel-group controlled trial aims to investigate the consequence of early trauma on dopamine release evoked by positive valence odors.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Aged 18 years or older * Have been selected based on the Childhood Trauma Questionnaire score * Non-smoker * Be able to speak and read French * Sign a consent form before intervention. Exclusion Criteria: * A pre-existing condition that affects olfaction including congenital anosmia, upper respiratory tract infection, nasal and/or sinus disease, * Be on medication, with the exception of oral contraceptives * Pregnant or breast-feeding woman (check with urine pregnancy tests); * Contraindications to TMS or MRI (implanted medical devices or metallic foreign body in the head); * Psychiatric disorders * Use of psychotropic drugs * Have participated in a study involving the injection of a radiotracer during the year
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What it tests

  • High score at Childhood Trauma Questionnaire.
  • Low score at Childhood Trauma Questionnaire.
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Where

1 site
CH le Vinatier
Bron, France
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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