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โ† Trials
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Canadian Bone Strength Development Study

Recruitingn/aAges 10 Years - 12 YearsAllUniversity of Saskatchewan
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In plain words

What the trial is, and whether it could suit you

The goal of this project is to learn about differences in bone development between children with and without type-1 diabetes (T1D). The main questions this study aims to answer are: 1. Assess how and when sex-specific bone developmental trajectories in the leg and arm will differ between children with T1D and control cohorts relative to the critical period of rapid skeletal growth in puberty. It is hypothesized that children with T1D will have inferior bone development, particularly lower gains in bone strength. 2. Assess why bone trajectories differ between T1D and control cohorts by identifying the role of body composition, site-specific muscle force and physical activity on differences in bone properties in female and male children with and without T1D. It is hypothesized that children with T1D will have lower gains in lean mass, muscle force, number of daily bone impacts and minutes

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Children with Type-I Diabetes: Inclusion Criteria * Females: 10-11 years old. * Males: 11 - 12 years old. * Diagnosed with type-1 diabetes for at least 6 months. * Capacity to give informed consent (patient and parent/guardian). Children with the capacity to give assent will do so in addition to parental consent. Exclusion Criteria * Consuming any medications or have additional illnesses associated with bone health, osteoporosis (including renal disease, celiac disease, hypogonadism, hyperthyroidism) or altered physical growth (precocious puberty). * Have gone through adolescent growth spurt at study entry. Control Group (Typically Developing Children): Inclusion Criteria * Females: 10-11 years old. * Males: 11 - 12 years old. * Capacity to give informed consent (patient and parent/guardian). Children with the capacity to give assent will do so in addition to parental consent. Exclusion Criteria * Have an illness or are taking medications influencing bone health or physical growth. * Evidence of pathologic low trauma or vertebral fracture(s). * Have gone through adolescent growth spurt at study entry.
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What it tests

  • Not listed
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Where

1 site
University of Saskatchewan
Saskatoon, Canada
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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