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Green Propolis Extract and Royal Jelly in Hypertensive Patients and/or With Chronic Kidney Disease

RecruitingNAAges 18 Years - 75 YearsAllUniversidade Federal Fluminense
NCT06288204 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This work aims to evaluate the effects of the association of green propolis extract with royal jelly on inflammation and oxidative stress in participants with chronic kidney diseases (CKD) and Systemic arterial hypertension (SAH), in a longitudinal, randomized, double-blind, placebo-controlled clinical trial that will be carried out for 2 months.

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📋 Eligibility rules (as published)
Inclusion Criteria: * patients in stages 3 and 5 of CKD (GFR from 15 to 59 mL/min), * patients receiving ambulatorial nutrition treatment at least 6 months * patients on regular Hemodialysis treatment for at least 6 months * patients using one to three antihypertensive drugs Exclusion Criteria: * autoimmune and infectious diseases, * diabetes * cancer * AIDS * pregnant women * patients using catabolic drugs or antibiotics; * patients with catheter access to hemodialysis; * patients using antioxidant vitamin supplements, prebiotics, probiotics, symbiotic, * Patients on regular intake of propolis who are allergic to corn starch or report being allergic to bee stings. * patients with acute myocardial infarction (AMI) and/or cerebrovascular accident (CVA)
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What it tests

  • Propolis associated with Royal Jelly
  • Royal Jelly
  • Placebo
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Where

2 sites
Denise Mafra
Rio de Janeiro, Brazil
Denise Mafra
Rio de Janeiro, Brazil
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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