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Efficacy and Safety of Topical Tranexamic Acid (TXA) Administration Cementless Bipolar Hemiarthroplasty for Femoral Neck Fracture - a Randomized Controlled Trial

RecruitingNAAges 60 Years - anyAllKing Chulalongkorn Memorial Hospital
NCT06289478 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The goal of this Randomized controlled trial is to evaluate in household ambulatory, elderly patients sustaining femoral neck fracture who are subjected to be treat with cementless bipolar hemiarthroplasty. The main questions it aims to answer are: * The efficacy in reducing blood transfusion for topical tranexamic acid administration * The safety of tranexemic acid, topically used As having undergone bipolar hemiarthroplasty surgery, participants will either receive retrograde intraarticular tranexamic acid injection via drain tube, or topical soaking administration. Researchers will compare, with standard procedure (procedure), whether topically administered tranexamic acid would reduce rate of blood transfusion.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Elderly patients (age \> 60 years) * Femoral neck fractures from low energy mechanism * Household ambulator * Undergoing cementless bipolar hemiarthroplasty at KCMH * Informed consent Exclusion Criteria: * Allergy to TXA * History of VTE * History of hip surgery, pathological fracture, hip infection * Congenital or acquired coagulopathy * Hb \< 10 g/dL or Platelet \< 140,000
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What it tests

  • Retrograde Intraarticular Injection via Drain Tube
  • Topical Soaking of Tranexamic Acid
  • Placebo Comparator: Standard procedure (placebo)
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Where

2 sites
Faculty of Medicine, King Chulalongkorn Memorial Hospital
Bangkok, Thailand
Faculty of Medicine
Bangkok, Thailand
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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