AI Cure is a research tool showing open data. Not medical advice. Discuss with your doctor. Terms

โ† Trials
๐Ÿงช

Non-invasive Measurement of the Hypotension Prediction Index for the Reduction of Intraoperative Hypotension

RecruitingNAAges 45 Years - anyAllUniversity of Giessen
๐Ÿ’ฌ

In plain words

What the trial is, and whether it could suit you

In order to reduce the incidence of IOH, various goal-directed therapy (GDT) protocols have already been introduced with success regarding the reduction of postoperative AKI and MINS. However, these studies used an invasive hemodynamic monitoring which offered a continuous surveillance of the blood pressure. In contrast, standard non-invasive blood pressure monitoring results in a blind gap between two measurements (mostly three or five minutes). In order to address this limitation, different continuous non-invasive blood pressure monitoring devices have been introduced. The next evolutional step of non-invasive cardiac output monitoring was to prevent IOH before their onset by using the Hypotension Prediction Index (HPI). Based on the Edward ฬs monitoring platform, HPI is a monitoring tool which aims to predict IOH (defined as MAP\<65 mmHg for at least one minute) up to 15 min before it

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * Patients undergoing major trauma or orthopedic surgery in supine position, which is defined as: * Reconstructive Surgery of the pelvis (e.g., stabilization of fractures) * Total hip arthroplasty * Surgery of the proximal femur (e.g., stabilization of fractures) * Total knee arthroplasty * Surgery of the spine * Performance of general anesthesia with planned duration of \&gt;90min * Age โ‰ฅ 45 years Exclusion Criteria: \- Predefined exclusion criteria are: * Planned invasive blood pressure monitoring * Participation in another interventional study * Pregnancy and nursing mothers * Surgery without controlled mechanical ventilation * ASA I or IV * Arterial Fibrillation * Allergy against gelantine
๐Ÿ’Š

What it tests

  • GDT-based hemodynamic management based on Clearsight device
๐Ÿ“

Where

1 site
Justus-Liebig-University of Giessen
Giessen, Germany
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
๐Ÿ›ก๏ธ

AI Cure shows public evidence (Open Targets, ClinicalTrials.gov, PubMed, openFDA, DepMap, AlphaFold) with its source, and AI summaries that cite it โ€” not medical advice and not a cure. Treatment decisions belong with your doctor. Research ideas are shared only with approved researchers and labs, who can test them. In an emergency call your local emergency number (112 in India and Europe, 911 in the US). AI Cure Terms of Use ยท Privacy