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Impact of Keratinized Mucosa Augmentation on Treatment Outcomes of Peri-implant Mucositis

RecruitingNAAges 18 Years - anyAllBiruni University
NCT06305000 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This study aims to observe the effects of keratinized mucosa width on peri-implant tissues by evaluating clinical and biochemical parameters. The main question it aims to answer is: Would increasing the width of the keratinized mucosa with free gingival graft (FGG) in peri-implant mucositis be beneficial in terms of clinical periodontal parameters and peri-implant crevicular fluid levels of inflammatory cytokines compared to non-surgical therapy alone? Our study consists of 4 groups: Peri-implant healthy group with sufficient keratinized mucosa (≥ 2mm) (n=16), peri-implant mucositis group with sufficient keratinized mucosa (n=16), peri-implant mucositis group with insufficient keratinized mucosa (\< 2mm) receiving only non-surgical treatment (n=16), peri-implant mucositis group with insufficient keratinized mucosa receiving FGG in addition to non-surgical treatment (n=16). Clinical an

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📋 Eligibility rules (as published)
Inclusion Criteria: * Individual dental implants with a fixed prosthetic restoration that has been functional for at least 1 year * No systemic disease and medication use that may affect periodontal or peri-implanter tissues * Not receiving periodontal treatment in the last 6 months * Volunteering to participate in the study Exclusion Criteria: * Prosthetic restorations with an excessive contour which do not allow peri-implant pocket measurement * Being pregnant or breastfeeding, * Autoimmune and/or inflammatory diseases of the oral cavity, * Active periodontal disease * Smokers (≥ 10 cigarettes per day) * Improperly positioned implants
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What it tests

  • Non-surgical treatment
  • Free gingival graft
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Where

1 site
Biruni University
Istanbul, Turkey (Türkiye)
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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