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Comparative Study of New Classification and Traditional Classification of Radioactive Oropharyngeal Mucositis

Recruitingn/aAges 18 Years - anyAllNanfang Hospital, Southern Medical University
NCT06307327 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Radiation oropharyngeal mucositis is one of the most painful side effects of radiotherapy in patients with head and neck tumors. However, the traditional radioactive oropharyngeal mucositis grading system has the problem of poor evaluation consistency. To solve this problem, we innovatively classify radiation oropharyngeal mucositis into four types according to the four-stage histopathological changes of acute radiation injury: (1) congestive; (2) Scattered erosion type; (3) Fusion erosion type; (4) Ulcer type. We intend to conduct a multicenter observational cohort study to compare the consistency of different physicians in the assessment of radiation oropharyngeal mucositis with new and traditional classifications, and to explore changes in blood markers of different types of oropharyngeal mucositis using clinical residual blood samples.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Voluntarily sign informed consent; * Age 18 or older on the date of signing the informed consent; * Histologically confirmed head and neck tumor, radiotherapy or chemoradiotherapy. Exclusion Criteria: * They also have other uncontrolled serious medical conditions, such as unstable heart disease requiring treatment, poorly controlled diabetes (fasting blood glucose \> 1.5× the upper limit of normal), mental illness, and a history of severe allergies
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What it tests

  • Not listed
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Where

4 sites
Southern medical university
Guangzhou, China
Huizhou Central People's Hospital
Huizhou, China
Jieyang people's hospital
Jieyang, China
Meizhou People's Hospital, Meizhou Academy of Medical Sciences Meizhou
Meizhou, China
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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