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Multidimensional Evaluation of Patients' Affected by Obstructive Apnea Syndrome (OSAS) Before and After Ventilotherapy

Recruitingn/aAges 20 Years - 60 YearsAllIstituto Auxologico Italiano
NCT06312956 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This observational study aims to evaluate multiple dimensions of health in patients with Obstructive Sleep Apnea Syndrome (OSAS), before and after three weeks of ventilotherapy. Specifically, the study aims to identify pre- vs post-treatment differences in the following domains: * cognitive performance * blood expression of biomarkers related to neurodegeneration * psychosocial wellbeing Thus, patients will complete the following evaluations before (T0) and after (T1) ventilotherapy: * neuropsychological standard assessment * blood sampling * psychosocial self-reported questionnaires

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📋 Eligibility rules (as published)
Inclusion Criteria: * OSAS diagnosis (AHI \> 5) * handedness: right Exclusion Criteria: * previous ventilotherapy * neurological and/or neurodegenerative conditions * Personality disorders, autism spectrum disorders, schizophrenia, psychosis * sleep disorders comorbidities (eg., narcolepsy)
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What it tests

  • Continuous Positive Airway Pressure Ventilotherapy
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Where

1 site
IRCCS Istituto Auxologico Italiano
Piancavallo, Italy
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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