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โ† Trials
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Transplanting Lungs From Uncontrolled Donation After Circulatory Death

RecruitingNAAges 18 Years - anyAllNYU Langone Health
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In plain words

What the trial is, and whether it could suit you

The study team developed an uncontrolled donation after circulatory death (uDCD) protocol that preserves lungs for just over 3 hours after death using positive end expiratory pressure (PEEP) and supplemental oxygen. The study will assess lung uDCD program safety by continuous review of operations/clinical records from each case activation and transplantation. Attrition outcomes include rates of initial and continued lung preservation, donation authorization, lung recovery, passing ex-vivo lung perfusion (EVLP) performance testing, and lung transplantation. Planned viability assessments also include macroscopic determination, radiology (X-ray), and fiber optic bronchoscopy before initiating EVLP. We expect \~50% of lungs assessed with EVLP will be transplanted to meet sustainability targets. Safety outcomes include the primary outcome, primary graft dysfunction (PGD) grade III at 72 hours

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * Patients waiting for lung transplants * Willing to participate in the research study Exclusion Criteria: * Unable to be followed for 1 year after transplantation * Unable to provide written informed consent to participate in the research (or designate a surrogate)
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What it tests

  • Lung uDCD Protocol
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Where

1 site
NYU Langone Health
New York, United States
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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