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Imaging in Moyamoya Disease - Study to Investigate Different Imaging Technologies for a Better Understanding of Various Imaging Techniques to Evaluate Cerebral Hemodynamics, Disease-activity and Possibly the Etiology in Moyamoya Patients

RecruitingNAAges 18 Years - 80 YearsAllUniversity Hospital Tuebingen
NCT06330818 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Aim of this study is to improve patient care in Moyamoya Patients by improving Imaging technologies and aiming to identify factors involved in disease progression. Main tasks are: * Analysis of CO2-triggered BOLD fMRI for analysis of cerebral hemodynamics in comparison to H2 15O PET/CT * Analysis of longitudinal changes of contrast enhancement in vessel-wall imaging and correlation of disease activity with biosampling * Definition of a standardized recommendation for pre- and postoperative imaging of Moyamoya patients

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📋 Eligibility rules (as published)
Inclusion Criteria: * Patients with suspicion of Moyamoya Disease * Patients able to understand the study and to give their informed consent Exclusion Criteria: * Cerebral vascular disease caused by atherosclerosis * Vasculitis * Contraindications to MRI * Contraindications to PET/CT * Pregnancy * Inability to give informed consent * Renal insufficiency
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What it tests

  • MRI
  • H2 15O PET/CT
  • Biosampling
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Where

1 site
University of Tuebingen, Neurosurgery
Tübingen, Germany
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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