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Cardiometabolic Function in Offspring, Mother and Placenta After Assisted Reproductive Technology

Recruitingn/aAges 18 Years - 40 YearsAllCopenhagen University Hospital, Rigshospitalet
NCT06334003 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The overall objective is to establish the first-of-its-kind longitudinal cohort of pregnant women, biological fathers/partners and offspring from pregnancies achieved by frozen embryo transfer (FET), fresh-embryo transfer (fresh ET) and naturally conceived (NC) to investigate maternal cardiometabolic profiles, fetal growth patterns and placental function during pregnancy as well as metabolic and endocrine health in the offspring. Additionally, the aim is to explore genetic and epigenetic patterns in placenta, fetus and parents. As secondary objectives, the investigator group will examine telomere length and minipuberty hormones in children born after FET, fresh-ET and NC.

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📋 Eligibility rules (as published)
Inclusion Criteria: Pregnant women who have either had fertility treatment at Rigshospitalet or Herlev Hospital (FET and fresh ET groups) or are scheduled for prenatal ultrasounds at Rigshospitalet or Herlev Hospital (NC group) will be screened for eligibility. Inclusion must happen before their routine ultrasound scan in 1. trimester. Exclusion Criteria: * Maternal pregestational diabetes type 1 or 2 * Non-singleton pregnancies * Maternal pregestational BMI \> 35 kg/m2 * Severe maternal co-morbidity * Oocyte donation
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What it tests

  • Not listed
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Where

3 sites
Fertility Clinic, Rigshospitalet, Copenhagen University Hospital
Copenhagen, Denmark
Department of Fetalmedicin, Herlev Hospital
Copenhagen, Denmark
Dept. of Paediatric and Adolescent Medicine, Herlev Hospital
Copenhagen, Denmark
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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