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The Clinical Effect of Sugammadex Sodium (Domestic) for Antagonizing Neuromuscular Blockade After Thoracic Surgery

RecruitingNAAges 19 Years - 75 YearsAllThe Fourth Affiliated Hospital of Zhejiang Univerโ€ฆ
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In plain words

What the trial is, and whether it could suit you

This study aims to compare the use of sugammadex (domestic) and neostigmine for antagonism after thoracic surgery, and observe the effect of sugammadex (domestic) on neuromuscular blockade antagonism after thoracic surgery, in order to provide a basis for optimizing the use of muscle relaxants and their antagonists during anesthesia.

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: 1. Patients who undergo elective lung surgery under general anesthesia and require endotracheal intubation; 2. Age\>18 years old, gender not limited; 3. American Society of Anesthesiologists ASA Level I-III; 4. Use rocuronium bromide for neuromuscular blockade; 5. The patient voluntarily participated in the trial. Exclusion Criteria: 1. The patient explicitly refused to participate in this trial; 2. Family history of malignant hyperthermia, patients with allergies to sodium sulbactam, neostigmine ingredients and their excipients, and patients with allergies to drugs used during general anesthesia; 3. Patients with tracheal malformations or suspected difficult airways, coagulation dysfunction, severe liver and kidney dysfunction, and severe lung disease; 4. Patients who are not extubated and sent to the ward or ICU after surgery; 5. The researchers believe that patients with any other unfavorable factors to participate in this trial.
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What it tests

  • SUGAMMADEX SODIUM 100 Mg in 1 mL
  • Neostigmine
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Where

1 site
The Fourth Affiliated Hospital of Zhejiang University School of Medicine
Yiwu, China
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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