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Autoantibodies Against-nephrin in Idiopathic Nephrotic Syndrome

Recruitingn/aAges 18 Years - anyAllMario Negri Institute for Pharmacological Research
NCT06334692 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This retrospective study is aimed at evaluating the levels of circulating anti-nephrin autoantibodies in patients with INS, including those with MCD/FSGS and in patients who have experienced relapse of FSGS post-transplant, compared to those of a control group of patients with nephrotic syndrome due to primary membranous nephropathy (MN).

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📋 Eligibility rules (as published)
Inclusion Criteria: * Adult (\>18 years) males and females * Patients with biopsy-proven idiopathic MCD or FSGS (cases) * Patients with biopsy-proven idiopathic membranous nephropathy (controls) * Patients who provided consent to store their samples in the certified CRB biobank Exclusion Criteria: * Reasonable possibility of a secondary cause of NS (for cases) or MN (for controls) at time of blood collections * Active viral or bacterial infections at time of blood collections
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What it tests

  • In-house ELISA, and ELISA kits from "DBA Italy" (Abbexa).
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Where

1 site
Clinical Research Center for Rare Disease Aldo e Cele Daccò
Ranica, Italy
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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