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Obstructive Colon Cancer, a Bridge to Surgery in Right Sided Obstructive Colon Cancer

Recruitingn/aAges 18 Years - anyAllAmphia Hospital
NCT06338332 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Rationale: Approximately 13% (range 10-28%) of all colorectal cancer patients (CRC) present with an acute obstruction. Postoperative mortality after an emergency resection is known for its high risk of morbidity and mortality. Different options can be considered in the management of obstructing right sided CRC: 1) primary resection, simultaneous treatment of obstruction and tumour resection, or 2) staged treatment of the obstruction with secondary resection of the tumour. Currently, in the Netherlands, an emergency resection has been judged to be inferior to postponing surgery. Patients who present with right sided obstructive colon cancer at one of the participating hospitals are subjected to a bridge to surgery (BTS) protocol. Objective: The primary objective of this study is to determine the feasibility of BTS protocols in right sided obstructive colon cancer and reduce mortality- an

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📋 Eligibility rules (as published)
Inclusion Criteria: * Patients age is 18 years or older * Patients presenting with symptoms of obstruction (including cecum, ascending colon, hepatic flexure, transverse colon, splenic flexure, descending colon, sigmoid colon) caused by (high suspicion or histologically proven) colonic cancer. * Patient presenting with symptoms of partial obstruction (abdominal pain, nausea, vomiting, diarrhoea) confirmed by the presence of a dilated colon or ileum with a computed tomography (CT-scan). * Treatment with curative intent. Exclusion Criteria: * Obstruction of the colon pathologically caused by benign disease. * Obstruction of the colon caused by an extra-colonic malignancy. * Suspicion of emergency complications caused by peritonitis due to perforation (tumour or blow out) or sepsis. * Patients with advanced disease who will undergo a palliative trajectory. * Rectal cancer
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What it tests

  • Not listed
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Where

1 site
Amphia Hospital
Breda, Netherlands
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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