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Noninvasive Evaluation of Fetal Hyperinsulinemia With Ultrasound Radiomics

Recruitingn/aAges 18 Years - 45 YearsFemaleTurku University Hospital
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In plain words

What the trial is, and whether it could suit you

The goal of this observational study is to compare fetal liver ultrasound radiomics between pregnancies complicated by type 1 diabetes and healthy controls. The main questions it aims to answer are: * Are fetal liver ultrasound radiomic features reproducible? * Does fetal liver ultrasound radiomics differ between pregnancies complicated by type 1 diabetes and healthy controls? Participants will undergo ultrasound examination to collect ultrasound data for the analyses.

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * Age between 18-45 years * Capable to give an informed consent * Singleton pregnancy * Planning to deliver in Turku University Hospital * Maternal BMI \< 40 * Gestational age should be confirmed by first trimester ultrasound * Normal oral glucose tolerance test (OGTT) at 24-28 gestational weeks in controls Exclusion Criteria: * Major fetal chromosomal, genetic, or structural anomaly * Fetal growth restriction, or birth weight \< 10th centile * Birth weight \> 90th centile or polyhydramnios in the controls * Non-reassuring fetal status requiring immediate treatment, or intrauterine fetal demise * Verified fetal infection (e.g. cytomegalovirus, toxoplasma, hepatitis B and C), excluding bacterial infection due to intrapartum chorioamnionitis * Placenta accreta spectrum disorder * Major maternal medical condition requiring systemic pharmacological treatment, other than non-severe hypertension, hypothyroidism, asthma, mild psychiatric disorders, etc. * Alcohol or tobacco use, or substance abuse in pregnancy
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What it tests

  • Not listed
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Where

2 sites
Turku University Hospital
Turku, Finland
Turku University Hospital
Turku, Finland
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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