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The Clinical Study of 3D-printed Magnesium Alloy Prosthesis With Controllable Degradation Rate in the Repair of Periarticular Bone Defects

RecruitingNAAges 18 Years - 80 YearsAllPeking University Third Hospital
NCT06349629 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Perimarticular fracture bone defect is a common and complicated clinical disease. The current treatment for this type of injury is anatomical reduction of the fracture, where the bone defect is filled with artificial, autologous or allogeneic bone in granular form, and then fixed with plates and screws. However, these bone filler materials exist in a loose accumulation state and cannot form an effective overall support force for the joint. The applicant realized three dimensional (3D) printing of WE43 magnesium alloy with personalized design and porous overall structure, and developed high-temperature heat treatment technology to slow its degradation, which effectively realized the dual stability of degradation rate of magnesium alloy support body and overall structure during the bone repair period. This project will optimize the design of 3D printed WE43 magnesium alloy full-structure i

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📋 Eligibility rules (as published)
Inclusion Criteria: 1. Patients with traumatic periarticular fractures of extremities with bone defects requiring bone grafting mainly include distal radius fractures, proximal humerus fractures, and tibial plateau fractures. 2. Between the ages of 18 and 70. 3. Sign informed consent, voluntarily participate in the study, and complete postoperative follow-up. 4. There are no obvious surgical contraindications and no contraindications for magnesium alloy prosthesis implantation. Exclusion Criteria: * Patients with pathological fracture ② pregnant women ③ doctors evaluated other conditions that were not suitable for inclusion
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What it tests

  • 3D printed WE43 magnesium alloy
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Where

2 sites
Peking University Third Hospital
Beijing, China
Peking University Third Hospita
Beijing, China
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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