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Postop Pain Management in Pituitary Tumour Patients

RecruitingPhase 4Ages 18 Years - 100 YearsAllHamilton Health Sciences Corporation
NCT06353529 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

To assess the benefit of using an additional nerve block during minimally invasive pituitary surgery, to improve pain management after surgery. The medication (Bupivacaine) or a placebo (saline) will be injected during surgery and patients will be asked about their level of pain at multiple time points in the first 24 hours following surgery. Some patients will be randomized to a third, sham group that do not receive any additional injection. The aim is to improve patient outcomes and reduce the need for pain medication after surgery.

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📋 Eligibility rules (as published)
Inclusion Criteria: * adult patients (18 yrs or older) * undergoing endonasal pituitary adenoma resection Exclusion Criteria: * Patients with pre-existing chronic pain conditions requiring antidepressants (serotonin reuptake inhibitors), benzodiazepines, gabapentin, or opioid drugs * contraindications to the performance of SPGB such as known allergy to used medications * chronic alcohol abuse * uncontrolled systemic arterial hypertension * severe kidney or liver diseases * cardiomyopathies or sustained cardiac arrhythmias (permanent paroxystic atrial fibrillation or other sustained supraventricular rhythmic anomalies)
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What it tests

  • Bupivacaine-Epinephrine 0.5%-1:200,000 Injectable Solution
  • Placebo
  • Sham Comparator
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Where

1 site
Hamilton General Hospital
Hamilton, Canada
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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