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Reduced Stent Strategy Versus Conventional Percutaneous Coronary Revascularization in Patients Presenting With STEMI

RecruitingNAAges 18 Years - anyAllHospital Universitario La Fe
NCT06353594 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The objective is to compare a reduced stent strategy based on drug-coated balloon (DCB) percutaneous coronary intervention (PCI) with conventional drug-eluting stent (DES) coronary revascularization in patients presenting with ST-segment myocardial infarction (STEMI). Randomization will be performed after successful culprit-lesion guidewire crossing and flow restoration. Random allocation in a 1:1 fashion to one of the following strategies: * Study group: reduced stent PCI strategy (DCB-based) * Control group: conventional PCI strategy (DES-based).

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📋 Eligibility rules (as published)
Inclusion Criteria: \- Patients presenting with STEMI and indication to undergo pPCI. Exclusion Criteria: * Life expectancy \<1 year due 1 to non-cardiac disease. * Inability to provide informed consent. * Cardiogenic shock. * Left ventricular ejection fraction \<15%. * Left main disease. * Stent thrombosis * Patients with prior bypass graft lesions requiring PCI (culprit or non culprit lesions). * Patients with chronic total occlusions. * Untreatable coronary disease. * Non-identified culprit lesion. * Known allergy to aspirin, ticagrelor, prasugrel, clopidogrel, paclitaxel or sirolimus.
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What it tests

  • Primary PCI
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Where

23 sites
Hospital Universitario Juan Ramón Jiménez
Huelva, Spain
Hospital Universitario Y Politecnico La Fe
Valencia, Spain
Complejo Hospitalario Universitario de A Coruña
A Coruña, Spain
Hospital Universitario de Burgos
Burgos, Spain
Consorcio Hospitalario Provincial de Castellon
Castelló, Spain
Hospital Universitario Reina Sofía de Córdoba
Córdoba, Spain
Hospital General Universitario de Elche
Elche, Spain
Hospital Universitario Clínico San Cecilio
Granada, Spain

…and 15 more on ClinicalTrials.gov.

🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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