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Genetic Architecture of Acute Aortic Syndromes and Aortic Aneurysm.

Recruitingn/aAges 18 Years - anyAllUniversity Hospital, Basel, Switzerland
NCT06353607 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The aim of this study is to explore the genetic information associated with the development of TAA and aAD in individuals without history or syndromic features (Marfan syndrome, Ehlers-Danlos syndrome, Turner syndrome etc.) for aortic disease. For this purpose, whole genome sequencing will be performed in patients with documented aortic aneurysm or/and aortic dissection.

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📋 Eligibility rules (as published)
Inclusion Criteria: * All adult patients \> 18 years who underwent surgery for aAD or TAA intervention at the University Hospital Basel, starting in 2015. * All patients who will undergo surgery for aAD or TAA at the University Hospital Basel, beginning in 2024. Exclusion Criteria: * Patients will be excluded if they are not able or not willing to provide informed consent. * Patients with diagnosed heritable vascular disorders, such as Marfan syndrome, Turner Syndrome, Loeyes Dietz and Ehlers-Danlos syndrome.
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What it tests

  • Not listed
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Where

1 site
University Hospital Basel
Basel, Switzerland
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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