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Adolescent Dysmenorrhoea as a Risk Factor for Chronic Pain: Clinical Cohort Study

Recruitingn/aAges 11 Years - 20 YearsFemaleUniversity of Oxford
NCT06353789 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This study aims to understand whether changes in a variety of body systems which are seen in adult women with period pain are also seen in adolescents in the first few years of having periods. This information will help to understand 1) how quickly any changes occur, informing clinical practice, and 2) how period pain might lead to other types of chronic pain, potentially allowing development of preventative strategies.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Participant (or parent/guardian of participant) is willing and able to give informed consent for participation in the study. * Female or assigned female at birth. * aged 11 - 20 years. * At least 6 periods per year since menarche. * During the study data collection period will be within one of the following time intervals since menarche: * 12 - 15 months * 36 - 39 months * 60 - 63 months * Reports either period pain or no pain with periods and scores appropriately on NRS (period pain: ≥4/10; no period pain: ≤3/10). * Not using hormonal therapies (i.e. contraceptives) currently and has not used previously. * Reasonably fluent in English. Exclusion Criteria: * Current or previous chronic pain condition other than dysmenorrhoea, including migraine. * Pregnant or breast-feeding. * Previous cancer diagnosis. * Contraindication to MRI
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What it tests

  • Not listed
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Where

1 site
University of Oxford
Oxford, United Kingdom
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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