🌐 EnglishEN

AI Cure is a research tool showing open data. Not medical advice. Discuss with your doctor. Terms

← Trials
🧪

Unclassified GENotypes of Autoinflammatory Diseases and AA Amyloidosis

Recruitingn/aAges 3 Years - 80 YearsAllAssistance Publique - Hôpitaux de Paris
NCT06354322 on ClinicalTrials.gov ↗
💬

In plain words

What the trial is, and whether it could suit you

Patients with autoinflammatory diseases (AID) have recurrent episodes of systemic inflammation accompanied by nonspecific elevation of blood inflammation markers typically absent between attacks. A complication of autoinflammatory diseases is AA amyloidosis, which can lead to renal failure and dialysis. Advances in genetic analysis have led to the identification of new autoinflammatory diseases and thus new pathophysiological pathways. However, genetic analyses are sometimes confronted with results that are difficult to interpret. These are the Variants of Unknown Significance, for which genetic analysis alone does not allow to determine if the genetic mutation is responsible for the symptoms. genetic analysis sometimes has limitations in the diagnosis of AID which can only be overcome by pathophysiological studies of the variants found.

Sign in to get the eligibility rules as simple questions to take to your doctor.

Sign in
📋 Eligibility rules (as published)
Inclusion Criteria: Inclusion criteria for patients to be studied: * Patients over 18 years of age with the capacity to give express free and informed consent and; * Minor patients under 18 years of age with both parents or legal guardians giving consent; * Patients with unclassified IAD or AA amyloidosis of undetermined etiology; * Patients followed in one of the study departments; * Patients weighing more than 15 kg. Inclusion criteria for control patients: * Patients over 18 years of age with the capacity to give free and informed express consent; * Patients with IAD classified with well-defined international criteria or ; * Patients who have undergone cosmetic surgery or blood donors). Exclusion Criteria: * Patients unable to give express free and informed consent; * Subjects under guardianship, curatorship or safeguard of justice; * Subjects who do not speak French; * Subjects unable to answer questions or express themselves; * Patients weighing less than 15 kg; * Patients without social security coverage
💊

What it tests

  • Not listed
📍

Where

1 site
Service médecine interne-Hôpital Tenon
Paris, France
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
🛡️

AI Cure shows public evidence (Open Targets, ClinicalTrials.gov, PubMed, openFDA, DepMap, AlphaFold) with its source, and AI summaries that cite it — not medical advice and not a cure. Treatment decisions belong with your doctor. Research ideas are shared only with approved researchers and labs, who can test them. In an emergency call your local emergency number (112 in India and Europe, 911 in the US). AI Cure Terms of Use · Privacy