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The Relationship Between Controlling Risk Factors and Cerebral Haemodynamics in Lacunar Stroke

Recruitingn/aAges 18 Years - anyAllUniversity of Leicester
NCT06354881 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The goal of this observational study is to look at differences in brain blood flow before and after management of risk factors such as high blood pressure and diabetes in patients with lacunar stroke. Participants will be asked to undergo a simple brain blood flow assessment at their initial appointment, whereby they will be asked to sit and stand twice. The patients will then be asked for a follow-up assessment 4 weeks after, identical to the first. This will allow us to look at any changes in brain blood flow from before management of risk factors and 4 weeks after management of risk factors.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Adults aged between 18-120 years. * Diagnosis of lacunar stroke syndrome. * New diagnosis or known diagnosis of hypertension and/or diabetes. Exclusion Criteria: * Those who lack capacity can have a personal consultee consent to the study if they can still perform study requirements such as the sit-stand manoeuvre. Those who either cannot perform the manoeuvre or do not have a personal consultee to allow them to consent, are not able to take part. * Those with poorly controlled medical comorbidities affecting cerebral haemodynamics. (eg., heart failure).
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What it tests

  • Transcranial Doppler Ultrasonography (TCD) during sit-stand manoeuvres
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Where

1 site
University Hospitals of Leicester NHS Trust
Leicester, United Kingdom
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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