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Ultrahypofractionated, Adaptive Radiation Therapy of Prostate Cancer

Recruitingn/aAges 18 Years - 120 YearsMaleJena University Hospital
NCT06355050 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

In this prospective, multi-center cohort study, the tolerability and quality of life during ultrahypofractionated radiotherapy (RT) of early stage prostate cancer is surveyed at several institutions in Germany. Radiotherapy is delivered by an online-adaptive RT device (Varian Ethos), which is able to correct daily variations in anatomy and to adjust the irradiation plan accordingly. A digital patient questionnaire is used to asses quality of life longitudinally. Quality of life (QoL) and toxicity profiles will be correlated with planning parameters and compared to retrospective cohorts of patients who underwent normofractionated RT or moderately hypofractionated RT, respectively.

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📋 Eligibility rules (as published)
Inclusion Criteria: * no androgen deprivation therapy within the last 2 months prior to RT * good performance status (Eastern Cooperative Oncology Group, ECOG, 0/1) * no secondary malignancy
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What it tests

  • Not listed
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Where

1 site
Department of Radiotherapy and Radiation Oncology, Jena University Hospital
Jena, Germany
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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