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OverTTuRe: Characteristics, Treatment Patterns and Outcomes of Patients With ATTR Amyloidosis

Recruitingn/aAges any - anyAllAstraZeneca
NCT06355934 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The overall aim of this observational study is to generate real-world evidence on the pre- and post-diagnosis disease journeys, including baseline characteristics, treatment patterns and selected clinical, economic, and humanistic outcomes (for example Health Related Quality of Life (HRQoL), Neuropathy impairment score, activities of daily living (ADL) assessments) in patients with ATTR amyloidosis, and to better understand how the disease is presented.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Patients aged \>18 years at study index date AND * A reported diagnosis code for amyloidosis OR * A claim for ATTR-specific treatment OR * A positive biopsy for amyloidosis and positive immunostaining result of biopsy for ATTR Exclusion Criteria: * Evidence of primary (AL) and secondary (AA) amyloidosis AND/OR * At least one claim/procedure code for stem cell transplant or at least two claims/procedure codes for chemotherapy and autoimmune disease drugs which may represent AL (primary) or AA (secondary) amyloidosis treatments
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What it tests

  • no intervention
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Where

29 sites
Research Site
Eden Prairie, United States
Research Site
Calgary, Canada
Research Site
Beijing, China
Research Site
Changsha, China
Research Site
Chengdu, China
Research Site
Guangzhou, China
Research Site
Wuhan, China
Research Site
Horsens, Denmark

…and 21 more on ClinicalTrials.gov.

🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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