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โ† Trials
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Effects of Different Inhaled Oxygen Concentrations on Lung Function in Older Patients After Laparoscopic Gastrointestinal Surgery Under General Anesthesia

RecruitingPhase 4Ages 65 Years - anyAllChina Medical University, China
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In plain words

What the trial is, and whether it could suit you

This was a multicenter, prospective, parallel-grouping, randomized controlled clinical study comparing low FiO2 (40%) and high FiO2 (80%) levels in older patients undergoing laparoscopic gastrointestinal surgery.

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * Age not less than 65 years * American Society of Anesthesiologists grades I-III * No history of drug allergies or abnormal anesthesia. * The duration of mechanical ventilation was expected to be more than 2 hours. * Laparoscopic Gastrointestinal Surgery * The preoperative oxygen saturation was not less than 94%. * The patients will be planned to extubate in the operating room. Exclusion Criteria: * History of acute lung injury or acute respiratory distress syndrome (ARDS) within 3 months. * Cardiac function Class IV (New York Heart Association classification) * Chronic renal failure (renal cell filtration rate \<30 ml min-11.73/m2), severe liver disease * Patients with blurred consciousness and cognitive dysfunction * Severe coagulation dysfunction. * Without preoperative oxygen inhalation, blood oxygen level \<94%, and severe pulmonary dysfunction * Patients with endotracheal tubes were admitted to the intensive care unit (ICU) after surgery. * Body mass index (BMI) \>30kg/m2 * Inability to complete the study
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What it tests

  • 80% Oxygen
  • 40% Oxygen
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Where

16 sites
the First Hospital of China Medical University
Shenyang, China
Beijing Friendship Hospital, Capital Medical University
Beijing, China
Sichuan Provincial People's Hospital
Chendu, China
Chifeng Municipal Hospital
Chifeng, China
Dalian Third People's Hospital
Dalian, China
First Affiliated Hospital, Dalian Medical University
Dalian, China
First Affiliated Hospital of Harbin Medical University
Harbin, China
Harbin Medical University Cancer Hospital
Harbin, China

โ€ฆand 8 more on ClinicalTrials.gov.

๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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