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Improving the Success Rate for Thoracic Radiotherapy Through Specific Cardiac Substructure Dosimetry: Location Matters. (LOCATION MATTERS)

Recruitingn/aAges any - anyAllFondazione IRCCS Istituto Nazionale dei Tumori, M…
NCT06361784 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The prospective study LOCATION MATTERS aims to investigate the radiation-induced damage to the heart and the cardiovascular system in patients treated with thoracic radiotherapy. Patients enrolled in the study will complete a set of extensive measures at the baseline, end of RT, and 9 months after treatment. Ultrasound exams, CT scans, pulmonary tests and wearable devices will assess functional and morphological parameters and the association with their variation and the dose delivered to the heart substructures and to the normal lung.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Patients with NSCLC * Patients with locally advanced disease (Stage 3) * Patients treated with RT at Fondazione IRCCS Istituto Nazionale dei Tumori Exclusion Criteria: * Previous thoracic radiotherapy * Previous heart surgery
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What it tests

  • Not listed
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Where

1 site
Fondazione IRCCS Istituto Nazionale dei Tumori
Milan, Italy
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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