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99mTc-CNDG SPECT/CT in Brain Tumors

RecruitingNAAges 18 Years - anyAllPeking Union Medical College Hospital
NCT06362304 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The goal of this clinical trial is to evaluate the value of 99mTc-CNDG for diagnosis of brain tumors by comparing it with 18F-FDG-PET. The main questions it aims to answer are: 1. What is the diagnostic consistency between 99mTc-CNDG and 18F-FDG? 2. What is the correlation between the SUVmax value of 99mTc-CNDG and tumor type? Participants will: Receive18F-FDG-PET and 99mTc-CNDG examination within 2 weeks before surgery. Obtain pathological diagnosis by surgery or biopsy as the gold standard.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Patients with clinical diagnosis of brain tumor; * Be at least 18 years old; * The final pathological results could be obtained by surgery or biopsy; * Informed consent and the ability to be followed up; * Those who did not meet the exclusion criteria. Exclusion Criteria: * Insulin-dependent diabetes mellitus or fasting blood glucose \>7 mmol/L before 99mTc-CNDG injection; * Severe liver or kidney disease (serum creatinine level \>3.0mg/dL or any liver enzyme level ≥ 5 times the upper limit of normal); * Severe hypersensitivity or hypersensitivity to radiocontrast agents; * Claustrophobia (inability to undergo SPECT/CT or PET/CT scans); * Patients receiving radiotherapy and chemotherapy; * Being pregnant or breastfeeding.
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What it tests

  • 99mTc-CNDG SPECT/CT
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Where

1 site
Peking Union Medical College Hospital
Beijing, China
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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