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A Study on Relationship Between Resected Normal Liver Parenchymal Volume（RNLV）and Post-Hepatectomy Liver Failure (PHLF)

Recruitingn/aAges any - anyAllNational Natural Science Foundation of China
NCT06366048 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The post-hepatotectomy liver failure (PHLF) is still the most worrisome complication of hepatic resection. Surgeons have always been making efforts to preoperatively predict PHLF using kinds of techniques, scoring systems, and variables. The investigators of this study tried to create an individual predictive model based on the variable, resected normal parenchymal volume (RNLV), then assessing the performance and value of the model in clinical practice.

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📋 Eligibility rules (as published)
Inclusion criteria: * selective hepatectomies; * histologically confirmed as HCC and ICC * complete and accessible data Exclusion criteria: * any history of Associated Liver Partition and Portal vein ligation for Staged hepatectomy (ALPPS) * any history of portal vein embolism (PVE) * any history of tumor rupture * emergency surgery * pathologically diagnosed with neither HCC nor ICC * concomitant resection of gastrointestinal organs, spleenectomy or other organs
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What it tests

  • the different definitions of PHLF according to 50-50 criteria and ISGLS criteria
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Where

3 sites
Mengchao Hepatobiliary Hospital of Fujian Medical University
Fujian, China
The Third Affiliated Hospital of Naval Medical University
Shanhai, China
Cancer Hospital Chinese Academy of Medical Sciences, Shenzhen, Mengchao Hepatobiliary Hospital of Fujian Medical University
Shenzhencun, China
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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