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Prediction Models for Complications After CRT in Esophageal Cancer

Recruitingn/aAges 18 Years - 100 YearsAllUniversity Medical Center Groningen
NCT06366828 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The aim of this project is to develop and validate NTCP-models for complications after nCRT (and surgical resection), that can be uses for model-based dose optimization for PhRT and PRT, and for model-based selection for PRT, in patients with esophageal cancer

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📋 Eligibility rules (as published)
Inclusion Criteria: * Tumor in the esophagus, histologically proven or suspect for esophageal carcinoma * WHO performance 0-2 * Age\>18years * No distant metastasis (M0) * Treated with nCRT and planned for or followed by an esophagectomy between 2015 and 2021 in one of the participating centers. Exclusion Criteria: * Sarcoma, neuro-endocrine or small cell carcinoma of the esophagus * Patients who underwent a surgical resection in a non-participating surgical center will be excluded
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What it tests

  • retrospective
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Where

8 sites
Radboud UMC
Nijmegen, Netherlands
Maastro clinic
Maastricht, Netherlands
Amsterdam UMC
Amsterdam, Netherlands
Erasmus MC
Rotterdam, Netherlands
Holland PTC
Delft, Netherlands
UMCG
Groningen, Netherlands
Zuyderland hospital
Heerlen, Netherlands
UMCU
Utrecht, Netherlands
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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